Conditions We Research


As a dynamic independently held clinical research site company, The ERG Network offers a deep bench of specialized expertise in more than 50 specific indications, with unparalleled capabilities in CNS studies.

Biomarkers have become a critical tool in speeding the success of clinical research trials, enabling researchers to precisely pinpoint target patient populations, inclusion and exclusion criteria, and optimal trial endpoints. ERG’s extensive experience testing biomarkers in diverse therapeutic areas helps streamline this process, accelerating the path to approval.

Demonstrated Expertise in Key Indications

  • Alzheimer’s disease/Mild Cognitive Impairment
  • First-in-man studies
  • Psychiatry
  • Special patient populations

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Nearly half of America’s adult population currently has impaired glucose metabolism. By 2050, one in three will have diabetes. Unless we do something. ERG is invested in helping stop this epidemic.

Demonstrated Expertise in Key Indications

  • Diabetes mellitus
  • Diabetes mellitus without mention of complication
  • Diabetic retinopathy
  • Diabetes with neurological manifestations
  • Diabetes with other specified manifestations
  • Diabetes with peripheral circulatory disorders
  • Diabetes with unspecified complication

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Phase I studies help researchers determine how a drug works, by understanding its clinical pharmacology. Having conducted over 2000 Phase I studies, ERG is known throughout the industry for excelling in these trials. Most Phase I studies are conducted in normal healthy volunteers (NHV); NHVs are also used as a cohort of a Phase I study in metabolic, neurologic, psychiatric, endocrine, and cardiac disorders. We have access to a wide range of healthy subject profiles, and, whatever your compound, we stand ready to help you explore its clinical pharmacology.

Demonstrated Expertise in Key Indications

  • Absolute Bioavailability
  • Bioequivalence
  • Cardiac Safety, Thorough QT/QTc
  • Drug-Drug Interaction
  • Elderly Healthy Cohorts in Proof-of-Concept/Proof-of-Mechanism
  • ETOH Interaction
  • First-to-File
  • First-in-Man
  • Food Effect
  • Patch Irritability
  • Pharmacokinetic/Pharmacodynamic
  • Relative Bioavailability
  • Tasting

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Infectious diseases are disorders caused by organisms — such as bacteria, viruses, fungi or parasites. Many organisms live in and on our bodies. They’re normally harmless or even helpful. But under certain conditions, some organisms may cause disease. Some infectious diseases can be passed from person to person.

Demonstrated Expertise in Key Indications
  • Covid-19
  • Smallpox
  • Respiratory syncytial virus (RSV)

As scientists continue unlocking the human genome, they discover new methods of diagnosing and treating neurological disease—and ERG is at the forefront of translating this basic research into clinical solutions by advancing neurological clinical research studies.

Demonstrated Expertise in Key Indications
  • ALS
  • Alzheimer’s Disease
  • Autism
  • Cognitive Impairment
  • Dementia
  • Epilepsy
  • Essential Tremor
  • Huntington’s Disease
  • Lewy Body Dementia
  • Migraine
  • Movement Disorders
  • Multiple Sclerosis
  • Parkinson’s Disease
  • Primary Degenerative Dementia
  • Seizure Disorders
  • Stuttering
  • Tardive Dyskinesia
  • Tourette’s Syndrome (adult and adolescent)
  • Vascular Dementia
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Pain management is a leading public health challenge; the current opioid epidemic underscores the critical need for new approaches to both chronic and acute pain. ERG stands ready, delivering the expertise, facilities, and access to patient populations needed to accelerate drug development in this area.

Demonstrated Expertise in Key Indications

  • Chronic Back and Neck Pain
  • Complex regional pain syndrome (CRPS)
  • Diabetic peripheral neuropathy (DPN)
  • Fibromyalgia
  • Neuropathic Pain
  • Osteoarthritis
  • Postherpetic Neuralgia (PHN)

Demonstrated Expertise in Post-Operative Pain Management Following Key Surgical Procedures

  • Abdominoplasty
  • Bariatric Surgery
  • Bunionectomy
  • Cesarean Section
  • Herniorrhaphy (Pediatric and Adult)
  • Hysterectomy
  • Third Molar Extraction
  • Total Hip Arthroplasty (THA)
  • Total Knee Arthroplasty (TKA)

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Pediatric clinical research studies add crucial insight to the specialized regulatory dosing and therapeutic approaches required for children. ERG’s pediatric experts understand the nuances of these FDA-mandated pediatric/adolescent trials, which, as a sub-specialty of adult trials, require both different protocols and different techniques. Our pediatric-focused sites are prepared to accelerate your pediatric/adolescent studies.

Demonstrated Expertise in Key Indications

  • ADHD
  • Autism
  • Bipolar Disorder
  • Diabetes
  • General Anxiety Disorder
  • GERD
  • Major Depressive Disorder
  • Migraine
  • Obesity
  • Pain
  • Schizophrenia
  • Tourette’s Syndrome

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ERG was founded with a focus on debilitating mental health issues—optimizing our investigational sites and patient recruitment strategies to advance important therapies and helping bring dozens of much-needed medicines to market.

Demonstrated Expertise in Key Indications
  • ADHD
  • Anxiety Disorders
  • Bipolar Disorder
  • Eating Disorders
  • Depressive Disorders
  • Obsessive Compulsive
  • Disorder
  • Opioid Use Disorder
  • Post-Traumatic Stress
  • Disorder
  • Schizoaffective
  • Disorder
  • Schizophrenia
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At least 40 million Americans suffer from chronic, long-term sleep disorders each year, and an additional 20 million experience occasional sleeping problems. ERG’s specialized sleep labs and expert staff are dedicated to partnering in both early- and late-phase sleep trials to advance new therapeutics to market.

ERG also works with clients who are assessing sleep disturbance as a secondary outcome measure in psychiatric and neurological disorders. Examples include sleep disturbance in schizophrenia, wakefulness in patients with mild to moderate Alzheimer’s disease, and insomnia related to major depressive disorder. ERG is uniquely positioned to conduct these complex inpatient trials given the flexibility of the facilities, the customized PSG bedrooms, and the extensive training of both the technicians and the clinical/medical teams.

Demonstrated Expertise in Key Indications

  • Chronic Fatigue Syndrome
  • Circadian Rhythm Disorders
  • Delayed Sleep Phase Syndrome
  • Idiopathic Hypersomnia
  • Insomnia
  • Narcolepsy
  • Restless Leg Syndrome
  • Sleep Apnea
  • Sleep disturbances as a comorbidity

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pediatric autism

Currently, there are no treatments for the core symptoms of Autism Spectrum Disorder (ASD). Children 17 and under may qualify for a clinical trial to help change that.

memory loss

 Free memory screenings are now available to help detect symptoms. Those who receive a free screening may be eligible to participate in ongoing clinical trials.


If you or someone you know is affected by depression, upcoming clinical trials may be an option. Learn more today!